Product Data Sheet
Deferoxamine-DBCO
Catalog No. A41625
Deferoxamine-DBCO is a bifunctional chelating agent that effectively binds to radioactive metals, such as 89Zr, via its deferoxamine (DFO) structure for radiolabeling applications. Additionally, it facilitates metal-free Huisgen cycloaddition reactions with azide-containing biomolecules, including siRNA and monoclonal antibodies, through its dibenzocyclooctyne (DBCO) moiety under bioorthogonal conditions. This reagent combines robust metal-chelating capabilities with specific bioorthogonal reactivity, making it suitable for targeted radioactive imaging studies in oncology research.
Chemical Information
| Catalog Num | A41625 |
|---|---|
| M. Wt | 848.00 |
| Formula | C44H61N7O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2359695-48-8 |
| Synonyms | DFO-DBCO |
| SMILES | CC(N(CCCCCNC(CCC(N(CCCCCNC(CCC(N(CCCCCNC(CCC(N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O)=O)O)=O)=O)O)=O)=O)O)=O |
Biological Activity
| Description | Deferoxamine-DBCO is a bifunctional chelating agent that effectively binds to radioactive metals, such as 89Zr, via its deferoxamine (DFO) structure for radiolabeling applications. Additionally, it facilitates metal-free Huisgen cycloaddition reactions with azide-containing biomolecules, including siRNA and monoclonal antibodies, through its dibenzocyclooctyne (DBCO) moiety under bioorthogonal conditions. This reagent combines robust metal-chelating capabilities with specific bioorthogonal reactivity, making it suitable for targeted radioactive imaging studies in oncology research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
