Product Data Sheet

Trequinsin hydrochloride

Catalog No. A41772

main product photo
Trequinsin hydrochloride is a highly potent inhibitor of platelet cyclic adenosine monophosphate (cAMP) phosphodiesterase (PDE), exhibiting an IC50 value of 0.25 nM. This compound effectively prevents the aggregation of human platelets induced by various agonists, including ADP, collagen, thrombin, and epinephrine. Trequinsin hydrochloride serves as a valuable tool for research applications focused on platelet function and the modulation of vascular responses.
Chemical Information
Catalog NumA41772
M. Wt441.95
FormulaC24H28ClN3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.78416-81-6
SynonymsHL 725
SMILESO=C(N(CCC1=C2C=C(OC)C(OC)=C1)C2=C/3)N(C)C3=N\C4=C(C)C=C(C)C=C4C.[H]Cl
Biological Activity
DescriptionTrequinsin hydrochloride is a highly potent inhibitor of platelet cyclic adenosine monophosphate (cAMP) phosphodiesterase (PDE), exhibiting an IC50 value of 0.25 nM. This compound effectively prevents the aggregation of human platelets induced by various agonists, including ADP, collagen, thrombin, and epinephrine. Trequinsin hydrochloride serves as a valuable tool for research applications focused on platelet function and the modulation of vascular responses.
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SHIPPING AND STORAGE
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