Product Data Sheet
3-O-Methylquercetin
Catalog No. A41787
3-O-Methylquercetin is a potent inhibitor of phosphodiesterases (PDE), targeting both cAMP and cGMP pathways with IC50 values of 13.8 μM and 14.3 μM, respectively. This compound also inhibits β-secretase with an IC50 of 6.5 μM, showcasing its potential in neuroprotective research against oxidative neuronal damage. Furthermore, 3-O-Methylquercetin exhibits significant antiviral activity against poliovirus, coxsackievirus, and human rhinovirus, along with demonstrated anti-inflammatory and trachea-relaxing properties. Its diverse biological activities make it a valuable tool for studying inflammatory diseases and respiratory conditions such as asthma.
Chemical Information
| Catalog Num | A41787 |
|---|---|
| M. Wt | 316.26 |
| Formula | C16H12O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1486-70-0 |
| Synonyms | |
| SMILES | O=C1C(OC)=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13 |
Biological Activity
| Description | 3-O-Methylquercetin is a potent inhibitor of phosphodiesterases (PDE), targeting both cAMP and cGMP pathways with IC50 values of 13.8 μM and 14.3 μM, respectively. This compound also inhibits β-secretase with an IC50 of 6.5 μM, showcasing its potential in neuroprotective research against oxidative neuronal damage. Furthermore, 3-O-Methylquercetin exhibits significant antiviral activity against poliovirus, coxsackievirus, and human rhinovirus, along with demonstrated anti-inflammatory and trachea-relaxing properties. Its diverse biological activities make it a valuable tool for studying inflammatory diseases and respiratory conditions such as asthma. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
