Product Data Sheet
Orismilast
Catalog No. A41789
Orismilast is a selective inhibitor of phosphodiesterase 4 (PDE4) with oral bioavailability, primarily targeting the PDE4B and PDE4D subtype splice variants. It exhibits potent anti-inflammatory activity, making it a valuable tool for the investigation of inflammatory diseases and associated therapeutic pathways. Orismilast's specificity for PDE4 provides insights into its mechanisms in modulating intracellular signaling and inflammatory responses.
Chemical Information
| Catalog Num | A41789 |
|---|---|
| M. Wt | 510.29 |
| Formula | C19H15Cl2F2NO7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1353546-86-7 |
| Synonyms | LEO-32731 |
| SMILES | O=S1(CCC2(OC3=C(C=CC(C(CC4=C(C=[N+](C=C4Cl)[O-])Cl)=O)=C3O2)OC(F)F)CC1)=O |
Biological Activity
| Description | Orismilast is a selective inhibitor of phosphodiesterase 4 (PDE4) with oral bioavailability, primarily targeting the PDE4B and PDE4D subtype splice variants. It exhibits potent anti-inflammatory activity, making it a valuable tool for the investigation of inflammatory diseases and associated therapeutic pathways. Orismilast's specificity for PDE4 provides insights into its mechanisms in modulating intracellular signaling and inflammatory responses. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
