Product Data Sheet
DSR-141562
Catalog No. A41794
DSR-141562 is a selective inhibitor of phosphodiesterase 1 (PDE1), demonstrating a primary mechanism of action through the inhibition of PDE1B with an IC50 of 43.9 nM. This compound also exhibits lower affinity for PDE1A and PDE1C, with IC50 values of 97.6 nM and 431.8 nM, respectively. DSR-141562 is useful for investigating the positive and negative symptoms, as well as cognitive impairments associated with schizophrenia, making it a valuable tool in psychiatric research.
Chemical Information
| Catalog Num | A41794 |
|---|---|
| M. Wt | 414.42 |
| Formula | C19H25F3N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2007975-22-4 |
| Synonyms | |
| SMILES | O=C1N(C)C(OC[C@H]2CC[C@H](C(F)(F)F)CC2)=NN3C1=CN=C3C4CCOCC4 |
Biological Activity
| Description | DSR-141562 is a selective inhibitor of phosphodiesterase 1 (PDE1), demonstrating a primary mechanism of action through the inhibition of PDE1B with an IC50 of 43.9 nM. This compound also exhibits lower affinity for PDE1A and PDE1C, with IC50 values of 97.6 nM and 431.8 nM, respectively. DSR-141562 is useful for investigating the positive and negative symptoms, as well as cognitive impairments associated with schizophrenia, making it a valuable tool in psychiatric research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
