Product Data Sheet
Enoximone
Catalog No. A41800
Enoximone is a selective, orally active phosphodiesterase III (PDE3) inhibitor, exhibiting an IC50 of 5.9 μM. By inhibiting cGMP-inhibited PDE, it promotes vasodilation and elevates intracellular cAMP levels. Additionally, Enoximone demonstrates PDE4 inhibitory effects, with an IC50 of 21.1 μM for myocardial PDE4A. This compound is of significant interest for research into congestive heart failure, as well as for its potential bronchodilatory, antiasthma, and anti-inflammatory properties.
Chemical Information
| Catalog Num | A41800 |
|---|---|
| M. Wt | 248.30 |
| Formula | C12H12N2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 77671-31-9 |
| Synonyms | |
| SMILES | O=C1NC(C)=C(N1)C(C2=CC=C(C=C2)SC)=O |
Biological Activity
| Description | Enoximone is a selective, orally active phosphodiesterase III (PDE3) inhibitor, exhibiting an IC50 of 5.9 μM. By inhibiting cGMP-inhibited PDE, it promotes vasodilation and elevates intracellular cAMP levels. Additionally, Enoximone demonstrates PDE4 inhibitory effects, with an IC50 of 21.1 μM for myocardial PDE4A. This compound is of significant interest for research into congestive heart failure, as well as for its potential bronchodilatory, antiasthma, and anti-inflammatory properties. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
