Product Data Sheet
Mardepodect hydrochloride
Catalog No. A41806
Mardepodect hydrochloride is a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), exhibiting an IC50 value of 0.37 nM and demonstrating greater than 1000-fold selectivity over other phosphodiesterases. This compound has the ability to cross the blood-brain barrier, making it a valuable tool in neurological research. Its selective inhibition of PDE10A may provide insights into disorders such as schizophrenia and movement disorders, offering potential pathways for therapeutic development.
Chemical Information
| Catalog Num | A41806 |
|---|---|
| M. Wt | 428.91 |
| Formula | C25H21ClN4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2070014-78-5 |
| Synonyms | PF-2545920 hydrochloride |
| SMILES | CN1N=C(C2=CC=C(OCC3=NC4=CC=CC=C4C=C3)C=C2)C(C5=CC=NC=C5)=C1.Cl[H] |
Biological Activity
| Description | Mardepodect hydrochloride is a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), exhibiting an IC50 value of 0.37 nM and demonstrating greater than 1000-fold selectivity over other phosphodiesterases. This compound has the ability to cross the blood-brain barrier, making it a valuable tool in neurological research. Its selective inhibition of PDE10A may provide insights into disorders such as schizophrenia and movement disorders, offering potential pathways for therapeutic development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
