Product Data Sheet
KVA-D-88
Catalog No. A41810
KVA-D-88 is a potent phosphodiesterase 4 (PDE4) inhibitor, specifically targeting PDE4B and PDE4D with IC50 values of 140 nM and 880 nM, respectively. This compound readily crosses the blood-brain barrier and promotes cAMP accumulation, thereby modulating neuroactive substance-driven behaviors such as hyperlocomotion and locomotor sensitization. KVA-D-88 is valuable for research applications focused on drug addiction and related neurobiological processes.
Chemical Information
| Catalog Num | A41810 |
|---|---|
| M. Wt | 382.19 |
| Formula | C17H11Cl2F2N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2410550-31-9 |
| Synonyms | |
| SMILES | O=C(C1=CC2=CC=CN=C2N1C3=CC=C(Cl)C(Cl)=C3)N4CC(F)(F)C4 |
Biological Activity
| Description | KVA-D-88 is a potent phosphodiesterase 4 (PDE4) inhibitor, specifically targeting PDE4B and PDE4D with IC50 values of 140 nM and 880 nM, respectively. This compound readily crosses the blood-brain barrier and promotes cAMP accumulation, thereby modulating neuroactive substance-driven behaviors such as hyperlocomotion and locomotor sensitization. KVA-D-88 is valuable for research applications focused on drug addiction and related neurobiological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
