Product Data Sheet

Ophiobolin A

Catalog No. A41816

main product photo
Ophiobolin A is a potent inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase (PDE), exhibiting an IC50 value of 9 μM. This fungal metabolite, known for its phytotoxic properties, demonstrates significant antimicrobial and anticancer activities. Ophiobolin A is utilized in research applications exploring PDE inhibition and its effects on various cellular processes.
Chemical Information
Catalog NumA41816
M. Wt400.55
FormulaC25H36O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.4611-05-6
Synonyms
SMILESO=C/C1=C/C[C@]2([H])[C@@](CC[C@@]23O[C@@H](/C=C(C)\C)C[C@@H]3C)(C)C[C@@]4([H])[C@]1([H])C(C[C@]4(O)C)=O
Biological Activity
DescriptionOphiobolin A is a potent inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase (PDE), exhibiting an IC50 value of 9 μM. This fungal metabolite, known for its phytotoxic properties, demonstrates significant antimicrobial and anticancer activities. Ophiobolin A is utilized in research applications exploring PDE inhibition and its effects on various cellular processes.
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