Product Data Sheet
TAK-915
Catalog No. A41821
TAK-915 is a selective inhibitor of phosphodiesterase 2A (PDE2A) with an IC50 of 0.61 nM, demonstrating over 4100-fold selectivity for PDE2A compared to PDE1A. This brain-penetrant and orally active compound is of particular interest for research focused on neuropsychiatric and neurodegenerative disorders. Its unique mechanism of action positions TAK-915 as a valuable tool in the study of underlying pathways in these conditions.
Chemical Information
| Catalog Num | A41821 |
|---|---|
| M. Wt | 458.36 |
| Formula | C19H18F4N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1476727-50-0 |
| Synonyms | |
| SMILES | O=C(N1)CN(C(N[C@@H](C2=CC(F)=C(OC(F)(F)F)C=C2)COC)=O)C3=C1C=C(OC)C=N3 |
Biological Activity
| Description | TAK-915 is a selective inhibitor of phosphodiesterase 2A (PDE2A) with an IC50 of 0.61 nM, demonstrating over 4100-fold selectivity for PDE2A compared to PDE1A. This brain-penetrant and orally active compound is of particular interest for research focused on neuropsychiatric and neurodegenerative disorders. Its unique mechanism of action positions TAK-915 as a valuable tool in the study of underlying pathways in these conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
