Product Data Sheet
Roflupram
Catalog No. A41827
Roflupram is a selective phosphodiesterase 4 (PDE4) inhibitor that demonstrates oral bioavailability and effective central nervous system penetration, with an IC50 of 26.2 nM for human PDE4 core catalytic domains. This compound has been shown to reverse cognitive deficits and decrease the production of pro-inflammatory factors, making it valuable for research applications targeting neurological conditions and inflammation-related pathways.
Chemical Information
| Catalog Num | A41827 |
|---|---|
| M. Wt | 314.32 |
| Formula | C16H20F2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1093412-18-0 |
| Synonyms | |
| SMILES | CC(CC(C1=CC=C(C(OC2COCC2)=C1)OC(F)F)=O)C |
Biological Activity
| Description | Roflupram is a selective phosphodiesterase 4 (PDE4) inhibitor that demonstrates oral bioavailability and effective central nervous system penetration, with an IC50 of 26.2 nM for human PDE4 core catalytic domains. This compound has been shown to reverse cognitive deficits and decrease the production of pro-inflammatory factors, making it valuable for research applications targeting neurological conditions and inflammation-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
