Product Data Sheet
K134
Catalog No. A41828
K134 is a selective phosphodiesterase 3 (PDE3) inhibitor, demonstrating IC50 values of 0.1 µM for PDE3A and 0.28 µM for PDE3B. Inhibition of PDE3 leads to increased levels of cyclic AMP, which plays a crucial role in various physiological processes. This compound can be used in research applications focused on cardiovascular diseases, as well as in studies investigating the modulation of cellular signaling pathways associated with phosphodiesterase activity.
Chemical Information
| Catalog Num | A41828 |
|---|---|
| M. Wt | 399.48 |
| Formula | C22H29N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 189362-06-9 |
| Synonyms | OPC33509 |
| SMILES | O=C(NCCCOC1=CC2=C(NC(C=C2)=O)C=C1)N(C3CC3)[C@H]4[C@H](O)CCCC4 |
Biological Activity
| Description | K134 is a selective phosphodiesterase 3 (PDE3) inhibitor, demonstrating IC50 values of 0.1 µM for PDE3A and 0.28 µM for PDE3B. Inhibition of PDE3 leads to increased levels of cyclic AMP, which plays a crucial role in various physiological processes. This compound can be used in research applications focused on cardiovascular diseases, as well as in studies investigating the modulation of cellular signaling pathways associated with phosphodiesterase activity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
