Product Data Sheet
PDE5-IN-7
Catalog No. A41842
PDE5-IN-7 is a selective inhibitor of phosphodiesterase 5 (PDE5), demonstrating an IC50 value of 5 nM, and shows considerably lower activity against PDE1 with an IC50 of 300 nM. This compound exhibits potent biological activity in the modulation of intracellular cGMP levels, making it a valuable reagent for research focused on cardiovascular disorders and erectile dysfunction. Its specificity and efficacy make PDE5-IN-7 an important tool for understanding PDE5-related pathways.
Chemical Information
| Catalog Num | A41842 |
|---|---|
| M. Wt | 312.37 |
| Formula | C17H20N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 139756-21-1 |
| Synonyms | |
| SMILES | O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC=CC=C3OCC)N1 |
Biological Activity
| Description | PDE5-IN-7 is a selective inhibitor of phosphodiesterase 5 (PDE5), demonstrating an IC50 value of 5 nM, and shows considerably lower activity against PDE1 with an IC50 of 300 nM. This compound exhibits potent biological activity in the modulation of intracellular cGMP levels, making it a valuable reagent for research focused on cardiovascular disorders and erectile dysfunction. Its specificity and efficacy make PDE5-IN-7 an important tool for understanding PDE5-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
