Product Data Sheet
ent-Tadalafil
Catalog No. A41859
ent-Tadalafil is the inactive cis-enantiomer of the potent phosphodiesterase type 5 (PDE5) inhibitor (6R,12aS), which exhibits an IC50 of 0.090 μM. While ent-Tadalafil does not demonstrate significant biological activity, its characterization is essential for understanding the structure-activity relationship of PDE5 inhibitors. This compound serves as a reference material in biochemical research and may aid in the evaluation of enantiomeric effects on PDE5 inhibition.
Chemical Information
| Catalog Num | A41859 |
|---|---|
| M. Wt | 389.40 |
| Formula | C22H19N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 629652-72-8 |
| Synonyms | ent-IC-351 |
| SMILES | O=C([C@]1([H])CC2=C([C@H](C3=CC=C(OCO4)C4=C3)N15)NC6=C2C=CC=C6)N(C)CC5=O |
Biological Activity
| Description | ent-Tadalafil is the inactive cis-enantiomer of the potent phosphodiesterase type 5 (PDE5) inhibitor (6R,12aS), which exhibits an IC50 of 0.090 μM. While ent-Tadalafil does not demonstrate significant biological activity, its characterization is essential for understanding the structure-activity relationship of PDE5 inhibitors. This compound serves as a reference material in biochemical research and may aid in the evaluation of enantiomeric effects on PDE5 inhibition. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
