Product Data Sheet
PDE4-IN-24
Catalog No. A41866
PDE4-IN-24 is a highly potent inhibitor of phosphodiesterase 4D (PDE4D) with an IC50 value of 0.57 nM, demonstrating over 4100-fold selectivity against other phosphodiesterase families. This compound is relevant to research on inflammatory diseases, as it modulates cyclic nucleotide signaling pathways, which are critical for controlling inflammation and immune responses. Its specificity and activity make PDE4-IN-24 a valuable tool for studying the role of PDE4D in various biological contexts.
Chemical Information
| Catalog Num | A41866 |
|---|---|
| M. Wt | 432.44 |
| Formula | C20H18F2N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3087059-29-5 |
| Synonyms | |
| SMILES | O=C(NCC1=NC=CC=N1)C2=CSC(C3=CC=C(C(OCC4CC4)=C3)OC(F)F)=N2 |
Biological Activity
| Description | PDE4-IN-24 is a highly potent inhibitor of phosphodiesterase 4D (PDE4D) with an IC50 value of 0.57 nM, demonstrating over 4100-fold selectivity against other phosphodiesterase families. This compound is relevant to research on inflammatory diseases, as it modulates cyclic nucleotide signaling pathways, which are critical for controlling inflammation and immune responses. Its specificity and activity make PDE4-IN-24 a valuable tool for studying the role of PDE4D in various biological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
