Product Data Sheet
2',3'-Cyclic NADP disodium
Catalog No. A41872
2',3'-Cyclic NADP disodium serves as a substrate for phosphodiesterase (PDE), particularly 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), which is predominantly found in myelin. This compound has been utilized in coupled enzyme assays for the precise quantification of CNP activity. Additionally, 2',3'-Cyclic NADP disodium (at a concentration of 5 μM) has demonstrated the ability to enhance calcium overload-induced calcium release and mitigate calcium-induced swelling in rat brain mitochondria, making it a valuable tool in neurobiological research.
Chemical Information
| Catalog Num | A41872 |
|---|---|
| M. Wt | 769.35 |
| Formula | C21H24N7Na2O16P3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 100929-77-9 |
| Synonyms | 2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate |
| SMILES | O=[P](O[P](OC[C@H]([C@H]1O)O[C@]([N+]2=CC=CC(C(N)=O)=C2)([H])[C@@H]1O)([O-])=O)(O[Na])OC[C@H]3O[C@](N4C5=NC=NC(N)=C5N=C4)([H])[C@@](O6)([H])[C@]3([H])O[P]6(O[Na])=O |
Biological Activity
| Description | 2',3'-Cyclic NADP disodium serves as a substrate for phosphodiesterase (PDE), particularly 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), which is predominantly found in myelin. This compound has been utilized in coupled enzyme assays for the precise quantification of CNP activity. Additionally, 2',3'-Cyclic NADP disodium (at a concentration of 5 μM) has demonstrated the ability to enhance calcium overload-induced calcium release and mitigate calcium-induced swelling in rat brain mitochondria, making it a valuable tool in neurobiological research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
