Product Data Sheet
RS-25344 hydrochloride
Catalog No. A41898
RS-25344 hydrochloride is a highly selective inhibitor of phosphodiesterase 4 (PDE 4), exhibiting an IC50 of 0.28 nM in human lymphocytes. The compound demonstrates minimal activity against PDE I, II, and III, with IC50 values exceeding 100 μM. RS-25344 hydrochloride possesses significant anti-inflammatory properties and has been shown to enhance memory and cognitive functions, as well as exhibiting potential antineoplastic effects. This makes it a valuable tool for research in areas related to inflammation, neurobiology, and cancer.
Chemical Information
| Catalog Num | A41898 |
|---|---|
| M. Wt | 411.80 |
| Formula | C19H14ClN5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 152815-28-6 |
| Synonyms | |
| SMILES | [H]Cl.O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O |
Biological Activity
| Description | RS-25344 hydrochloride is a highly selective inhibitor of phosphodiesterase 4 (PDE 4), exhibiting an IC50 of 0.28 nM in human lymphocytes. The compound demonstrates minimal activity against PDE I, II, and III, with IC50 values exceeding 100 μM. RS-25344 hydrochloride possesses significant anti-inflammatory properties and has been shown to enhance memory and cognitive functions, as well as exhibiting potential antineoplastic effects. This makes it a valuable tool for research in areas related to inflammation, neurobiology, and cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
