Product Data Sheet

Quazinone

Catalog No. A41904

main product photo
Quazinone is a selective inhibitor of cGMP-inhibited phosphodiesterase (PDE3), targeting the catalytic activity of this enzyme. It effectively inhibits the phosphorylation of p42/p44 MAP kinase, leading to decreased mitogenic signaling. Quazinone exhibits antimitogenic effects and is useful in studies related to cell proliferation and signal transduction pathways.
Chemical Information
Catalog NumA41904
M. Wt235.67
FormulaC11H10ClN3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.70018-51-8
SynonymsRo 13-6438; Ro 13-6438/006
SMILESC[C@H]1N2C(NC3=CC=CC(Cl)=C3C2)=NC1=O
Biological Activity
DescriptionQuazinone is a selective inhibitor of cGMP-inhibited phosphodiesterase (PDE3), targeting the catalytic activity of this enzyme. It effectively inhibits the phosphorylation of p42/p44 MAP kinase, leading to decreased mitogenic signaling. Quazinone exhibits antimitogenic effects and is useful in studies related to cell proliferation and signal transduction pathways.
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SHIPPING AND STORAGE
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