Product Data Sheet
PQ-10
Catalog No. A41907
PQ-10 is a potent inhibitor of Phosphodiesterase 10A (PDE10A), displaying an IC50 of 4.6 nM and an ED50 of 13 mg/kg. This compound influences patterns of brain glucose metabolism, potentially serving as a translational biomarker in neurological research. PQ-10 is particularly valuable for investigating psychiatric disorders, including schizophrenia, and provides insights into the underlying mechanisms of these conditions.
Chemical Information
| Catalog Num | A41907 |
|---|---|
| M. Wt | 403.43 |
| Formula | C22H21N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 927691-21-2 |
| Synonyms | |
| SMILES | COC1=CC(C(N(CC2)C[C@@H]2OC3=NC(C=CC=C4)=C4N=C3)=NC=N5)=C5C=C1OC |
Biological Activity
| Description | PQ-10 is a potent inhibitor of Phosphodiesterase 10A (PDE10A), displaying an IC50 of 4.6 nM and an ED50 of 13 mg/kg. This compound influences patterns of brain glucose metabolism, potentially serving as a translational biomarker in neurological research. PQ-10 is particularly valuable for investigating psychiatric disorders, including schizophrenia, and provides insights into the underlying mechanisms of these conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
