Product Data Sheet
(S)-Gebr32a
Catalog No. A41909
(S)-Gebr32a is a selective phosphodiesterase 4 (PDE4) inhibitor, demonstrating IC50 values of 19.5 µM for PDE4 cat and 2.1 µM for PDE4D3. It exhibits significant biological activity by modulating intracellular cyclic AMP levels, making it a valuable tool for investigating inflammatory processes and neurodegenerative diseases. This compound is suitable for research applications focused on the role of PDE4 in various cellular signaling pathways.
Chemical Information
| Catalog Num | A41909 |
|---|---|
| M. Wt | 437.48 |
| Formula | C22H29F2N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3055162-32-5 |
| Synonyms | |
| SMILES | FC(F)OC1=CC=C(C2=NN(C[C@@H](O)CN3CCOCC3)C=C2)C=C1OC4CCCC4 |
Biological Activity
| Description | (S)-Gebr32a is a selective phosphodiesterase 4 (PDE4) inhibitor, demonstrating IC50 values of 19.5 µM for PDE4 cat and 2.1 µM for PDE4D3. It exhibits significant biological activity by modulating intracellular cyclic AMP levels, making it a valuable tool for investigating inflammatory processes and neurodegenerative diseases. This compound is suitable for research applications focused on the role of PDE4 in various cellular signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
