Product Data Sheet
PDE2A-IN-2
Catalog No. A41982
PDE2A-IN-2 is a selective inhibitor of phosphodiesterase type 2A (PDE2A) with a Ki value of 5.49 nM, demonstrating over 100-fold selectivity against other PDE isoforms. This compound serves as a radiolabeled PET tracer, facilitating brain imaging in patients with neurodegenerative diseases by eliciting a signal specifically in PDE2A-rich regions. Its application in neurodegenerative disease research highlights its potential in studying PDE2A's role in pathophysiology.
Chemical Information
| Catalog Num | A41982 |
|---|---|
| M. Wt | 347.34 |
| Formula | C17H16F3N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055901-03-4 |
| Synonyms | |
| SMILES | CC1=NC2=C(C(NC3(C4=CC=C(C=C4)C(F)(F)F)CC3)=N1)C=NN2C |
Biological Activity
| Description | PDE2A-IN-2 is a selective inhibitor of phosphodiesterase type 2A (PDE2A) with a Ki value of 5.49 nM, demonstrating over 100-fold selectivity against other PDE isoforms. This compound serves as a radiolabeled PET tracer, facilitating brain imaging in patients with neurodegenerative diseases by eliciting a signal specifically in PDE2A-rich regions. Its application in neurodegenerative disease research highlights its potential in studying PDE2A's role in pathophysiology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
