Product Data Sheet
JNJ-42259152
Catalog No. A41987
JNJ-42259152 is a selective phosphodiesterase 10A (PDE10A) positron emission tomography (PET) tracer designed to assess PDE10A activity in vivo. This compound demonstrates reliable binding potential across critical brain regions, including the lentiform nucleus, caudate nucleus, and ventral striatum, making it a valuable tool in the exploration of neuropsychiatric disorders. With an average blood half-life of 90 minutes, JNJ-42259152 enables detailed kinetic analysis in healthy subjects, supporting research into the underlying mechanisms of various central nervous system conditions.
Chemical Information
| Catalog Num | A41987 |
|---|---|
| M. Wt | 402.46 |
| Formula | C24H23FN4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1301167-87-2 |
| Synonyms | |
| SMILES | CC1=CN=C(C(C)=C1)COC2=CC=C(C=C2)C3=NN(C=C3C4=CC=NC=C4)CCF |
Biological Activity
| Description | JNJ-42259152 is a selective phosphodiesterase 10A (PDE10A) positron emission tomography (PET) tracer designed to assess PDE10A activity in vivo. This compound demonstrates reliable binding potential across critical brain regions, including the lentiform nucleus, caudate nucleus, and ventral striatum, making it a valuable tool in the exploration of neuropsychiatric disorders. With an average blood half-life of 90 minutes, JNJ-42259152 enables detailed kinetic analysis in healthy subjects, supporting research into the underlying mechanisms of various central nervous system conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
