Product Data Sheet
BMS-341400
Catalog No. A41989
BMS-341400 is a potent, orally active selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 0.3 nM. By inhibiting PDE5, BMS-341400 effectively prevents the breakdown of cyclic guanosine monophosphate (cGMP), facilitating nitric oxide (NO)-induced smooth muscle relaxation in the corpus cavernosum, which promotes erectile function. This compound is primarily utilized in the study of erectile dysfunction and related pathways in sexual health research.
Chemical Information
| Catalog Num | A41989 |
|---|---|
| M. Wt | 491.93 |
| Formula | C23H22ClN9O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 296250-53-8 |
| Synonyms | |
| SMILES | CCN1C2=C(C3=C(C(N4C=C(C(NC)=O)N=C4)=NN=C3NCC5=CC(Cl)=C(OC)C=C5)C=N2)C=N1 |
Biological Activity
| Description | BMS-341400 is a potent, orally active selective phosphodiesterase 5 (PDE5) inhibitor with an IC50 of 0.3 nM. By inhibiting PDE5, BMS-341400 effectively prevents the breakdown of cyclic guanosine monophosphate (cGMP), facilitating nitric oxide (NO)-induced smooth muscle relaxation in the corpus cavernosum, which promotes erectile function. This compound is primarily utilized in the study of erectile dysfunction and related pathways in sexual health research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
