Product Data Sheet
ASP9436
Catalog No. A42013
ASP9436 is a potent and orally available inhibitor of phosphodiesterase 10A (PDE10A), exhibiting an IC50 of 8 nM against human PDE10A. This compound effectively reduces locomotor activity in mouse models of hyperactivity and improves visual recognition memory deficits in neonatal mice. ASP9436 is valuable for research focused on understanding and potentially treating schizophrenia.
Chemical Information
| Catalog Num | A42013 |
|---|---|
| M. Wt | 498.40 |
| Formula | C25H25Cl2N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1401807-89-3 |
| Synonyms | |
| SMILES | O=C1C=CC(C2=CN(C)N=C2COC3=CC=C(C4=CC=CC5=C4N=CN5C)C=C3)=CN1C.Cl.Cl |
Biological Activity
| Description | ASP9436 is a potent and orally available inhibitor of phosphodiesterase 10A (PDE10A), exhibiting an IC50 of 8 nM against human PDE10A. This compound effectively reduces locomotor activity in mouse models of hyperactivity and improves visual recognition memory deficits in neonatal mice. ASP9436 is valuable for research focused on understanding and potentially treating schizophrenia. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
