Product Data Sheet
ICI-63197
Catalog No. A42030
ICI-63197 is a dual inhibitor of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4), exhibiting Ki values of 9 µM and 10 µM, respectively. This compound demonstrates selectivity against PDE1 and PDE2, allowing for targeted modulation of cyclic nucleotide levels. ICI-63197 is noted for its antidepressant effects, making it a valuable tool for research into mood disorders and the underlying mechanisms of antidepressant action.
Chemical Information
| Catalog Num | A42030 |
|---|---|
| M. Wt | 207.23 |
| Formula | C9H13N5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 27277-00-5 |
| Synonyms | |
| SMILES | O=C1N(CCC)C2=NC(N)=NN2C=C1C |
Biological Activity
| Description | ICI-63197 is a dual inhibitor of phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4), exhibiting Ki values of 9 µM and 10 µM, respectively. This compound demonstrates selectivity against PDE1 and PDE2, allowing for targeted modulation of cyclic nucleotide levels. ICI-63197 is noted for its antidepressant effects, making it a valuable tool for research into mood disorders and the underlying mechanisms of antidepressant action. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
