Product Data Sheet

Ibudilast-d7

Catalog No. A42064

main product photo
Ibudilast-d7 is a deuterium-labeled derivative of Ibudilast, a selective phosphodiesterase (PDE) inhibitor that modulates cyclic AMP levels. This compound exhibits notable platelet anti-aggregatory effects and is relevant in asthma research due to its inhibitory impact on tracheal smooth muscle contractility. Furthermore, Ibudilast is investigated for its potential neuroprotective and anti-dementia properties, particularly in countering neurotoxicity associated with activated microglia.
Chemical Information
Catalog NumA42064
M. Wt237.35
FormulaC14H11D7N2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2713301-45-0
Synonyms
SMILESO=C(C1=C2C=CC=CN2N=C1C(C)C)C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H]
Biological Activity
DescriptionIbudilast-d7 is a deuterium-labeled derivative of Ibudilast, a selective phosphodiesterase (PDE) inhibitor that modulates cyclic AMP levels. This compound exhibits notable platelet anti-aggregatory effects and is relevant in asthma research due to its inhibitory impact on tracheal smooth muscle contractility. Furthermore, Ibudilast is investigated for its potential neuroprotective and anti-dementia properties, particularly in countering neurotoxicity associated with activated microglia.
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