Product Data Sheet
Torbafylline
Catalog No. A42086
Torbafylline is a potent phosphodiesterase (PDE) inhibitor that specifically targets the PDE4 pathway. It has been shown to reduce protein degradation in rat skeletal muscle following thermal injuries by activating the cAMP/EPAC/PI3K/Akt signaling pathway. Torbafylline effectively suppresses the heightened ubiquitin-proteasome-dependent protein breakdown associated with conditions such as cancer and sepsis in skeletal muscle, making it a valuable tool for research in muscle wasting and related disorders.
Chemical Information
| Catalog Num | A42086 |
|---|---|
| M. Wt | 338.40 |
| Formula | C16H26N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 105102-21-4 |
| Synonyms | HWA 448 |
| SMILES | O=C1C2=C(N(C)C(N1CCCCC(C)(C)O)=O)N=CN2COCC |
Biological Activity
| Description | Torbafylline is a potent phosphodiesterase (PDE) inhibitor that specifically targets the PDE4 pathway. It has been shown to reduce protein degradation in rat skeletal muscle following thermal injuries by activating the cAMP/EPAC/PI3K/Akt signaling pathway. Torbafylline effectively suppresses the heightened ubiquitin-proteasome-dependent protein breakdown associated with conditions such as cancer and sepsis in skeletal muscle, making it a valuable tool for research in muscle wasting and related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
