Product Data Sheet
JNJ-42314415
Catalog No. A42089
JNJ-42314415 is a selective phosphodiesterase 10A (PDE10A) inhibitor, demonstrating Ki values of 35 nM and 64 nM for human recombinant PDE10A and rat PDE10A, respectively. This compound plays a significant role in regulating intracellular signaling pathways through the modulation of cAMP and cGMP levels. JNJ-42314415 is valuable in research applications related to neurological disorders and potential therapeutic strategies for conditions such as schizophrenia and Parkinson's disease.
Chemical Information
| Catalog Num | A42089 |
|---|---|
| M. Wt | 353.42 |
| Formula | C19H23N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1334165-90-0 |
| Synonyms | |
| SMILES | CC1=C(N2C(C(N3CCOCC3)=NC=C2)=N1)C4=CC=C(N=C4)CCOC |
Biological Activity
| Description | JNJ-42314415 is a selective phosphodiesterase 10A (PDE10A) inhibitor, demonstrating Ki values of 35 nM and 64 nM for human recombinant PDE10A and rat PDE10A, respectively. This compound plays a significant role in regulating intracellular signaling pathways through the modulation of cAMP and cGMP levels. JNJ-42314415 is valuable in research applications related to neurological disorders and potential therapeutic strategies for conditions such as schizophrenia and Parkinson's disease. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
