Product Data Sheet
PDE4-IN-32
Catalog No. A42092
PDE4-IN-32 is a selective inhibitor of phosphodiesterase 4B (PDE4B) and phosphodiesterase 4D (PDE4D) with IC50 values of 13.7 nM and 23.8 nM, respectively. This compound effectively penetrates the blood-brain barrier and has demonstrated the ability to enhance recovery of motor and cognitive function in mouse models of middle cerebral artery occlusion (MCAO). Additionally, PDE4-IN-32 has been shown to reduce cerebral edema and is a valuable tool for research focused on ischemic stroke.
Chemical Information
| Catalog Num | A42092 |
|---|---|
| M. Wt | 320.34 |
| Formula | C20H16O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3080627-61-5 |
| Synonyms | |
| SMILES | COC1=C2C(C=C(O2)C3CC3)=C(C=C1)C4=CC=C5C(OCC5=C4)=O |
Biological Activity
| Description | PDE4-IN-32 is a selective inhibitor of phosphodiesterase 4B (PDE4B) and phosphodiesterase 4D (PDE4D) with IC50 values of 13.7 nM and 23.8 nM, respectively. This compound effectively penetrates the blood-brain barrier and has demonstrated the ability to enhance recovery of motor and cognitive function in mouse models of middle cerebral artery occlusion (MCAO). Additionally, PDE4-IN-32 has been shown to reduce cerebral edema and is a valuable tool for research focused on ischemic stroke. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
