Product Data Sheet
PDE5-IN-42
Catalog No. A42140
PDE5-IN-42 is a potent and orally active phosphodiesterase type 5 (PDE5) inhibitor, demonstrating an IC50 of 0.04 nM. This compound exhibits selectivity over PDE6 and PDE11, making it a valuable tool in research focused on vascular smooth muscle relaxation and erectile dysfunction. Its effectiveness in modulating cGMP levels supports its potential applications in cardiovascular disease studies and related therapeutic explorations.
Chemical Information
| Catalog Num | A42140 |
|---|---|
| M. Wt | 453.54 |
| Formula | C23H31N7O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 936449-28-4 |
| Synonyms | |
| SMILES | O=C(C1CCN(C2=NC(NC3=NC=CC(C)=C3)=C(N(CCOCC)N=C4CC)C4=N2)CC1)O |
Biological Activity
| Description | PDE5-IN-42 is a potent and orally active phosphodiesterase type 5 (PDE5) inhibitor, demonstrating an IC50 of 0.04 nM. This compound exhibits selectivity over PDE6 and PDE11, making it a valuable tool in research focused on vascular smooth muscle relaxation and erectile dysfunction. Its effectiveness in modulating cGMP levels supports its potential applications in cardiovascular disease studies and related therapeutic explorations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
