Product Data Sheet
PDM-042
Catalog No. A42147
PDM-042 is a selective inhibitor of phosphodiesterase 10A (PDE10A), demonstrating exceptional potency with IC50 values below 1 nM in both human and rat systems. It exhibits over 1000-fold selectivity against other phosphodiesterases, making it a valuable tool for investigating PDE10A's role in neurobiology. PDM-042 is particularly relevant for research into schizophrenia and related neurological disorders.
Chemical Information
| Catalog Num | A42147 |
|---|---|
| M. Wt | 406.48 |
| Formula | C21H26N8O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1404488-48-7 |
| Synonyms | |
| SMILES | CC1=NC=C(C)N2C1=NC(/C=C/C3=NC(N4CCCC4)=CC(N5CCOCC5)=N3)=N2 |
Biological Activity
| Description | PDM-042 is a selective inhibitor of phosphodiesterase 10A (PDE10A), demonstrating exceptional potency with IC50 values below 1 nM in both human and rat systems. It exhibits over 1000-fold selectivity against other phosphodiesterases, making it a valuable tool for investigating PDE10A's role in neurobiology. PDM-042 is particularly relevant for research into schizophrenia and related neurological disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
