Product Data Sheet
PDE4-IN-20
Catalog No. A42152
PDE4-IN-20 is a selective phosphodiesterase-4 (PDE4) inhibitor that operates at submicromolar concentrations and exhibits anti-TNF-α activity. This compound demonstrates significant biological effects both in vitro and in vivo, making it a valuable tool for research on inflammatory diseases. Molecular modeling studies highlight its binding interactions with PDE4, and conformational analyses confirm its pharmacological profile aligns with established PDE4 inhibitors. PDE4-IN-20 is useful for studies aimed at elucidating the role of PDE4 in cellular processes and therapeutic interventions.
Chemical Information
| Catalog Num | A42152 |
|---|---|
| M. Wt | 358.39 |
| Formula | C19H22N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1396397-03-7 |
| Synonyms | |
| SMILES | COC(C=C1/C=N/N(C)C(C2=CC(OC)=C(C=C2)OC)=O)=C(C=C1)OC |
Biological Activity
| Description | PDE4-IN-20 is a selective phosphodiesterase-4 (PDE4) inhibitor that operates at submicromolar concentrations and exhibits anti-TNF-α activity. This compound demonstrates significant biological effects both in vitro and in vivo, making it a valuable tool for research on inflammatory diseases. Molecular modeling studies highlight its binding interactions with PDE4, and conformational analyses confirm its pharmacological profile aligns with established PDE4 inhibitors. PDE4-IN-20 is useful for studies aimed at elucidating the role of PDE4 in cellular processes and therapeutic interventions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
