Product Data Sheet
Triflusal-d3
Catalog No. A42158
Triflusal-d3 is a deuterated derivative of Triflusal that serves as a stable isotope for analytical research. It functions as a dual inhibitor of Cyclooxygenase-1 (COX-1) and cAMP phosphodiesterase, demonstrating significant anti-inflammatory properties by inhibiting platelet aggregation and prostaglandin synthesis in ischemic tissues. Triflusal-d3 also enhances neutrophil nitric oxide production and promotes endothelial nitric oxide synthase (eNOS) expression. Its applications extend to the study of thromboembolic and ischemic cardiovascular diseases, as well as Alzheimer's disease models, providing insights into neurological and vascular pathologies.
Chemical Information
| Catalog Num | A42158 |
|---|---|
| M. Wt | 251.17 |
| Formula | C10H4D3F3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2748541-63-9 |
| Synonyms | |
| SMILES | O=C(O)C1=CC=C(C(F)(F)F)C=C1OC(C([2H])([2H])[2H])=O |
Biological Activity
| Description | Triflusal-d3 is a deuterated derivative of Triflusal that serves as a stable isotope for analytical research. It functions as a dual inhibitor of Cyclooxygenase-1 (COX-1) and cAMP phosphodiesterase, demonstrating significant anti-inflammatory properties by inhibiting platelet aggregation and prostaglandin synthesis in ischemic tissues. Triflusal-d3 also enhances neutrophil nitric oxide production and promotes endothelial nitric oxide synthase (eNOS) expression. Its applications extend to the study of thromboembolic and ischemic cardiovascular diseases, as well as Alzheimer's disease models, providing insights into neurological and vascular pathologies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
