Product Data Sheet
Parogrelil
Catalog No. A42161
Parogrelil is a potent phosphodiesterase (PDE) inhibitor, primarily targeting PDE3. It exhibits significant activity in reducing intermittent claudication by inhibiting platelet aggregation and vasoconstriction, leading to an improvement in walking distance and plantar surface temperature in experimental rat models. This compound is valuable for research in vascular biology and cardiology, particularly in studies related to peripheral artery disease and associated therapeutic interventions.
Chemical Information
| Catalog Num | A42161 |
|---|---|
| M. Wt | 449.73 |
| Formula | C19H18BrClN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 139145-27-0 |
| Synonyms | NT-702 free base; NT-702 free base |
| SMILES | O=C1C(Br)=C(NCC2=CC=CN=C2)C(OCCCC3=CC=C(Cl)C=C3)=NN1 |
Biological Activity
| Description | Parogrelil is a potent phosphodiesterase (PDE) inhibitor, primarily targeting PDE3. It exhibits significant activity in reducing intermittent claudication by inhibiting platelet aggregation and vasoconstriction, leading to an improvement in walking distance and plantar surface temperature in experimental rat models. This compound is valuable for research in vascular biology and cardiology, particularly in studies related to peripheral artery disease and associated therapeutic interventions. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
