Product Data Sheet
PDE5-IN-5
Catalog No. A42162
PDE5-IN-5 is a potent and selective inhibitor of phosphodiesterase 5 (PDE5), exhibiting an IC50 of 2.0 nM. This compound is utilized in research to investigate the modulation of cyclic guanosine monophosphate (cGMP) signaling pathways, which are implicated in various physiological processes such as vasodilation and erectile function. PDE5-IN-5 serves as a valuable tool in studies related to cardiovascular diseases and sexual dysfunction.
Chemical Information
| Catalog Num | A42162 |
|---|---|
| M. Wt | 482.33 |
| Formula | C23H20BrN3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2414921-33-6 |
| Synonyms | |
| SMILES | O=C(O)CCN(C1)C([C@@]2([H])CC3=C([C@@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O |
Biological Activity
| Description | PDE5-IN-5 is a potent and selective inhibitor of phosphodiesterase 5 (PDE5), exhibiting an IC50 of 2.0 nM. This compound is utilized in research to investigate the modulation of cyclic guanosine monophosphate (cGMP) signaling pathways, which are implicated in various physiological processes such as vasodilation and erectile function. PDE5-IN-5 serves as a valuable tool in studies related to cardiovascular diseases and sexual dysfunction. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
