Product Data Sheet

PyP-1

Catalog No. A42173

main product photo
PyP-1 is a potent and selective inhibitor of the phosphodiesterase 10A (PDE10A) enzyme, exhibiting a strong inhibitory effect with a Ki value of 0.32 nM. This compound has been shown to enhance cognitive behavior and is widely utilized in research focused on neurological conditions such as schizophrenia and cognitive impairment. Its specificity and efficacy make PyP-1 a valuable tool for investigating PDE10A's role in cognitive function and related disorders.
Chemical Information
Catalog NumA42173
M. Wt375.43
FormulaC20H21N7O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1370527-16-4
Synonyms
SMILESCN1N=CC(CNC2=CC(OC[C@@H]3[C@@H](C4=NC=CC=C4)C3)=NC5=CC=NN25)=C1
Biological Activity
DescriptionPyP-1 is a potent and selective inhibitor of the phosphodiesterase 10A (PDE10A) enzyme, exhibiting a strong inhibitory effect with a Ki value of 0.32 nM. This compound has been shown to enhance cognitive behavior and is widely utilized in research focused on neurological conditions such as schizophrenia and cognitive impairment. Its specificity and efficacy make PyP-1 a valuable tool for investigating PDE10A's role in cognitive function and related disorders.
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