Product Data Sheet
PDE4-IN-19
Catalog No. A42178
PDE4-IN-19 is a selective inhibitor of phosphodiesterase 4 (PDE4), demonstrating IC50 values of less than 10 nM for PDE4B1 and between 10-100 nM for PDE4D3. This compound plays a significant role in modulating intracellular levels of cyclic AMP, making it valuable for research on inflammatory diseases and neurological conditions. PDE4-IN-19 is useful in studying the effects of PDE4 inhibition on cellular signaling pathways and may aid in the development of therapeutics targeting these pathways.
Chemical Information
| Catalog Num | A42178 |
|---|---|
| M. Wt | 359.78 |
| Formula | C18H15ClFN3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3042879-82-0 |
| Synonyms | |
| SMILES | O=C1C2=C(C3=C(N2CCN1CCO)C=CC=N3)C4=CC(F)=C(Cl)C=C4 |
Biological Activity
| Description | PDE4-IN-19 is a selective inhibitor of phosphodiesterase 4 (PDE4), demonstrating IC50 values of less than 10 nM for PDE4B1 and between 10-100 nM for PDE4D3. This compound plays a significant role in modulating intracellular levels of cyclic AMP, making it valuable for research on inflammatory diseases and neurological conditions. PDE4-IN-19 is useful in studying the effects of PDE4 inhibition on cellular signaling pathways and may aid in the development of therapeutics targeting these pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
