Product Data Sheet
AMG580
Catalog No. A42192
AMG580 is a selective antagonist of phosphodiesterase 10A (PDE10A) with subnanomolar affinity across rat, primate, and human isoforms. This compound demonstrates significant biological activity in modulating intracellular signaling pathways associated with PDE10A inhibition. AMG580 is particularly useful in research applications involving noninvasive radiotracers, aiding in the exploration of brain imaging and neuropharmacology.
Chemical Information
| Catalog Num | A42192 |
|---|---|
| M. Wt | 473.50 |
| Formula | C26H24FN5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1227067-71-1 |
| Synonyms | |
| SMILES | O=C(C1=NC2=C(N1)C=CC=C2)C3=CC=C(C=C3)OC4=NC=CN=C4C5CCN(CC5)C(C(C)F)=O |
Biological Activity
| Description | AMG580 is a selective antagonist of phosphodiesterase 10A (PDE10A) with subnanomolar affinity across rat, primate, and human isoforms. This compound demonstrates significant biological activity in modulating intracellular signaling pathways associated with PDE10A inhibition. AMG580 is particularly useful in research applications involving noninvasive radiotracers, aiding in the exploration of brain imaging and neuropharmacology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
