Product Data Sheet

Pyrazole N-Desmethyl sildenafil

Catalog No. A42206

main product photo
Pyrazole N-Desmethyl sildenafil functions as an inhibitor of Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1). It demonstrates approximately 16% inhibition at a concentration of 100 µM. This compound is relevant for research into the pharmacological targeting of TbrPDEB1, which plays a role in the pathogenicity of Trypanosomiasis.
Chemical Information
Catalog NumA42206
M. Wt460.55
FormulaC21H28N6O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.139755-95-6
Synonyms
SMILESO=C1N=C(C2=C(OCC)C=CC(S(=O)(N3CCN(CC3)C)=O)=C2)NC4=C1NN=C4CCC
Biological Activity
DescriptionPyrazole N-Desmethyl sildenafil functions as an inhibitor of Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1). It demonstrates approximately 16% inhibition at a concentration of 100 µM. This compound is relevant for research into the pharmacological targeting of TbrPDEB1, which plays a role in the pathogenicity of Trypanosomiasis.
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