Product Data Sheet
LEO 29102
Catalog No. A42223
LEO 29102 is a potent inhibitor of phosphodiesterase 4 (PDE4) with an IC50 value of 5 nM. This compound effectively inhibits the release of TNFα, making it a valuable tool for studies related to inflammatory responses. LEO 29102 shows promise in the research of atopic dermatitis and other related conditions associated with PDE4 activity.
Chemical Information
| Catalog Num | A42223 |
|---|---|
| M. Wt | 441.31 |
| Formula | C20H22Cl2N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1035572-38-3 |
| Synonyms | |
| SMILES | COC1=C(C=CC(C(CC2=C(C=NC=C2Cl)Cl)=O)=C1OCC(NCCC)=O)OC |
Biological Activity
| Description | LEO 29102 is a potent inhibitor of phosphodiesterase 4 (PDE4) with an IC50 value of 5 nM. This compound effectively inhibits the release of TNFα, making it a valuable tool for studies related to inflammatory responses. LEO 29102 shows promise in the research of atopic dermatitis and other related conditions associated with PDE4 activity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
