Product Data Sheet

Desethyl sildenafil

Catalog No. A42225

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Desethyl Sildenafil is an impurity of Sildenafil, primarily known as a potent phosphodiesterase type 5 (PDE5) inhibitor, with an IC50 value of 5.22 nM. It serves as an important reference standard in the analysis of Sildenafil formulations and is utilized in the investigation of PDE5 inhibition. Research applications include quality control and pharmacokinetic studies related to Sildenafil.
Chemical Information
Catalog NumA42225
M. Wt446.52
FormulaC20H26N6O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.139755-91-2
SynonymsSildenafil impurity C
SMILESO=C1C(N(C)N=C2CCC)=C2N=C(C3=CC(S(=O)(N4CCN(C)CC4)=O)=CC=C3O)N1
Biological Activity
DescriptionDesethyl Sildenafil is an impurity of Sildenafil, primarily known as a potent phosphodiesterase type 5 (PDE5) inhibitor, with an IC50 value of 5.22 nM. It serves as an important reference standard in the analysis of Sildenafil formulations and is utilized in the investigation of PDE5 inhibition. Research applications include quality control and pharmacokinetic studies related to Sildenafil.
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