Product Data Sheet

Adibendan

Catalog No. A42235

main product photo
Adibendan (BM 14478) is a selective phosphodiesterase III (PDE III) inhibitor, exhibiting an IC50 value of 2.0 μM. With over 60-fold selectivity compared to PDE I and II inhibitors, Adibendan functions as a novel cardiotonic agent. This compound is valuable for researchers investigating cardiovascular diseases and exploring the modulation of cardiac contractility through PDE III inhibition.
Chemical Information
Catalog NumA42235
M. Wt278.31
FormulaC16H14N4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.100510-33-6
SynonymsBM 14478
SMILESO=C1NC2=CC3=C(C=C2C1(C)C)NC(C4=CC=NC=C4)=N3
Biological Activity
DescriptionAdibendan (BM 14478) is a selective phosphodiesterase III (PDE III) inhibitor, exhibiting an IC50 value of 2.0 μM. With over 60-fold selectivity compared to PDE I and II inhibitors, Adibendan functions as a novel cardiotonic agent. This compound is valuable for researchers investigating cardiovascular diseases and exploring the modulation of cardiac contractility through PDE III inhibition.
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