Product Data Sheet

Captopril-d3

Catalog No. A42339

main product photo
Captopril-d3 is a deuterium-labeled derivative of Captopril, a well-characterized competitive angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.025 μM. This stable isotope is utilized in the study of hypertension and congestive heart failure. Additionally, Captopril has been identified as an inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1), exhibiting an IC50 of 7.9 μM, making it valuable in antibiotic resistance research.
Chemical Information
Catalog NumA42339
M. Wt220.30
FormulaC9H12D3NO3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1356383-38-4
SynonymsSQ 14225-d3
SMILESOC([C@@]1(CCC([2H])(N1C([C@@H](CS)C)=O)[2H])[2H])=O
Biological Activity
DescriptionCaptopril-d3 is a deuterium-labeled derivative of Captopril, a well-characterized competitive angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 0.025 μM. This stable isotope is utilized in the study of hypertension and congestive heart failure. Additionally, Captopril has been identified as an inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1), exhibiting an IC50 of 7.9 μM, making it valuable in antibiotic resistance research.
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