Product Data Sheet
Moveltipril calcium
Catalog No. A42371
Moveltipril calcium is an orally active inhibitor of angiotensin-converting enzyme (ACE), demonstrating significant antihypertensive effects. It forms a stable thioester bond, exhibiting relative resistance to hydrolysis in liver homogenates. Moveltipril calcium effectively inhibits ACE activity extracted from rabbit lung in a concentration-dependent manner. Additionally, it selectively inhibits the contractile response to angiotensin-I in rat aortic rings and guinea pig ileum preparations, while enhancing the response to calcitonin, making it valuable for research in cardiovascular pharmacology and hypertension.
Chemical Information
| Catalog Num | A42371 |
|---|---|
| M. Wt | 417.51 |
| Formula | C19H29CaN2O5S.1/2Ca |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 85921-53-5 |
| Synonyms | MC-838 calcium |
| SMILES | O=C(C1CCCCC1)N[C@H](C)C(SC[C@@H](C)C(N2[C@@H](CCC2)C([O-])=O)=O)=O.[0.5].[Ca+2] |
Biological Activity
| Description | Moveltipril calcium is an orally active inhibitor of angiotensin-converting enzyme (ACE), demonstrating significant antihypertensive effects. It forms a stable thioester bond, exhibiting relative resistance to hydrolysis in liver homogenates. Moveltipril calcium effectively inhibits ACE activity extracted from rabbit lung in a concentration-dependent manner. Additionally, it selectively inhibits the contractile response to angiotensin-I in rat aortic rings and guinea pig ileum preparations, while enhancing the response to calcitonin, making it valuable for research in cardiovascular pharmacology and hypertension. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
