Product Data Sheet

Mal-PEG2-NHS ester

Catalog No. A42569

main product photo
Mal-PEG2-NHS ester is a non-cleavable antibody-drug conjugate (ADC) linker that features a maleimide group, a two-unit polyethylene glycol (PEG) spacer, and an N-hydroxysuccinimide (NHS) ester. This compound is essential for the efficient conjugation of cytotoxic agents to antibodies, facilitating targeted delivery in cancer therapy. Mal-PEG2-NHS ester enhances the stability and solubility of ADCs, making it suitable for research applications in drug development and discovery.
Chemical Information
Catalog NumA42569
M. Wt354.31
FormulaC15H18N2O8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1433997-01-3
Synonyms
SMILESO=C(ON1C(CCC1=O)=O)CCOCCOCCN2C(C=CC2=O)=O
Biological Activity
DescriptionMal-PEG2-NHS ester is a non-cleavable antibody-drug conjugate (ADC) linker that features a maleimide group, a two-unit polyethylene glycol (PEG) spacer, and an N-hydroxysuccinimide (NHS) ester. This compound is essential for the efficient conjugation of cytotoxic agents to antibodies, facilitating targeted delivery in cancer therapy. Mal-PEG2-NHS ester enhances the stability and solubility of ADCs, making it suitable for research applications in drug development and discovery.
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