Product Data Sheet

Methyl azetidine-3-carboxylate hydrochloride

Catalog No. A42588

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Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable linker for antibody-drug conjugates (ADCs) that facilitates the stable attachment of cytotoxic agents to antibodies. This compound also serves as an alkyl chain-based linker in the development of PROTACs (proteolysis-targeting chimeras), enabling targeted protein degradation. Its robust chemical properties make it essential for advancing research in targeted therapeutics and drug delivery systems.
Chemical Information
Catalog NumA42588
M. Wt151.59
FormulaC5H10ClNO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.100202-39-9
Synonyms
SMILESO=C(C1CNC1)OC.[H]Cl
Biological Activity
DescriptionMethyl azetidine-3-carboxylate hydrochloride is a non-cleavable linker for antibody-drug conjugates (ADCs) that facilitates the stable attachment of cytotoxic agents to antibodies. This compound also serves as an alkyl chain-based linker in the development of PROTACs (proteolysis-targeting chimeras), enabling targeted protein degradation. Its robust chemical properties make it essential for advancing research in targeted therapeutics and drug delivery systems.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.