Product Data Sheet
Azido-PEG5-alcohol
Catalog No. A42612
Azido-PEG5-alcohol functions as a non-cleavable linker in the synthesis of antibody-drug conjugates (ADCs) and as a versatile PEG-based linker for PROTAC (proteolysis-targeting chimeras) development. It is characterized by its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne, DBCO, or BCN-functionalized molecules. This reagent is instrumental in creating stable linkages for targeted protein degradation and therapeutic antibody conjugation, enhancing the efficacy of research applications in drug development.
Chemical Information
| Catalog Num | A42612 |
|---|---|
| M. Wt | 263.29 |
| Formula | C10H21N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 86770-68-5 |
| Synonyms | |
| SMILES | OCCOCCOCCOCCOCCN=[N+]=[N-] |
Biological Activity
| Description | Azido-PEG5-alcohol functions as a non-cleavable linker in the synthesis of antibody-drug conjugates (ADCs) and as a versatile PEG-based linker for PROTAC (proteolysis-targeting chimeras) development. It is characterized by its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne, DBCO, or BCN-functionalized molecules. This reagent is instrumental in creating stable linkages for targeted protein degradation and therapeutic antibody conjugation, enhancing the efficacy of research applications in drug development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
