Product Data Sheet
Azido-PEG3-Val-Cit-PAB-PNP
Catalog No. A42615
Azido-PEG3-Val-Cit-PAB-PNP is a cleavable polyethylene glycol (PEG)-based linker designed for use in antibody-drug conjugates (ADCs) and PROTAC synthesis. This reagent features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules and those with DBCO or BCN groups, respectively. Its versatile application in bioconjugation and targeted therapies makes it a valuable tool for advancing chemical biology research.
Chemical Information
| Catalog Num | A42615 |
|---|---|
| M. Wt | 773.79 |
| Formula | C34H47N9O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055047-18-0 |
| Synonyms | |
| SMILES | O=C(NC(C=C1)=CC=C1COC(OC(C=C2)=CC=C2[N](=O)=O)=O)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCN=[N+]=[N-])=O)=O |
Biological Activity
| Description | Azido-PEG3-Val-Cit-PAB-PNP is a cleavable polyethylene glycol (PEG)-based linker designed for use in antibody-drug conjugates (ADCs) and PROTAC synthesis. This reagent features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules and those with DBCO or BCN groups, respectively. Its versatile application in bioconjugation and targeted therapies makes it a valuable tool for advancing chemical biology research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
