Product Data Sheet
Cyclooctyne-O-NHS ester
Catalog No. A42637
Cyclooctyne-O-NHS ester is a versatile ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound features an alkyne group, allowing for efficient click chemistry applications, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its reactivity and cleavable nature make it an essential tool for developing targeted therapies in chemical biology and drug development.
Chemical Information
| Catalog Num | A42637 |
|---|---|
| M. Wt | 279.29 |
| Formula | C14H17NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1425803-45-7 |
| Synonyms | |
| SMILES | O=C(ON1C(CCC1=O)=O)COC2C#CCCCCC2 |
Biological Activity
| Description | Cyclooctyne-O-NHS ester is a versatile ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound features an alkyne group, allowing for efficient click chemistry applications, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its reactivity and cleavable nature make it an essential tool for developing targeted therapies in chemical biology and drug development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
