Product Data Sheet
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3
Catalog No. A42668
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable linker specifically designed for use in the development of antibody-drug conjugates (ADCs). This compound features an azide group that facilitates its application in click chemistry, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, making it versatile for conjugating with DBCO or BCN-containing compounds. It is an essential tool for enhancing the delivery and efficacy of therapeutic agents in targeted cancer therapies.
Chemical Information
| Catalog Num | A42668 |
|---|---|
| M. Wt | 1060.24 |
| Formula | C55H77N7O14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1224601-12-0 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C(CO)C=C1)[C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)CCCCNC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=CC=C4 |
Biological Activity
| Description | Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable linker specifically designed for use in the development of antibody-drug conjugates (ADCs). This compound features an azide group that facilitates its application in click chemistry, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, making it versatile for conjugating with DBCO or BCN-containing compounds. It is an essential tool for enhancing the delivery and efficacy of therapeutic agents in targeted cancer therapies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
